Genetic Accidents and Horizontal Transfers
This page explores the mechanisms of genome complexification, focusing on meiotic accidents (vertical transfers) and horizontal transfers in bacteria.
Definition: Vertical gene transfer refers to the transmission of genetic material from parent to offspring through reproduction.
Trisomy, a type of chromosomal abnormality, can occur due to abnormal meiosis. This process is illustrated with a diagram showing how a cell with 24 chromosomes can produce a gamete with an extra chromosome 21, leading to trisomy 21.
Example: Trisomy 21, also known as Down syndrome, is a well-known example of a chromosomal abnormality resulting from meiotic accidents.
Unequal crossing-over is another mechanism that contributes to genome complexification. This process can lead to gene duplication and the formation of multigene families.
Vocabulary: A multigene family is a group of genes that have evolved from a common ancestral gene through duplication and subsequent mutation.
The page also introduces three types of horizontal gene transfers in bacteria:
- Transformation
- Conjugation
- Transduction
Highlight: Horizontal gene transfer is a significant mechanism for genetic diversity in bacteria, allowing them to acquire new traits rapidly.
The diagram also mentions hormones related to the pituitary gland, including vasotocin (AVT), oxytocin (OT), and antidiuretic hormone (ADH), which are part of multigene families that have evolved through gene duplication and mutation.